MEC_ImpactReport_2025_with updated figures, no guidelines, LR - Flipbook - Page 13
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Jace’s story
Jace from Connecticut is one of the four children who
received life-changing treatment for his sight with
a pioneering new genetic medicine through Moorfields
Eye Hospital NHS Foundation Trust and UCL Institute of
Ophthalmology. The work was supported by the National
Institute for Health and Care Research (NIHR) and
Moorfields Eye Charity.
Jace has a rare genetic deficiency known as Leber
congenital amaurosis (LCA), and was born with only
sufficient sight to distinguish between light and dark. Most
children with the condition lose their sight as they get
older as the gene defect causes retinal cells to malfunction.
Jace received the new gene therapy at Moorfields in one of
his eyes, which since the treatment has retained much of
its vision.
Jace’s parents, Dani and Brendan, said,
We are so grateful for this opportunity, and
for the care he’s received; we feel we have friends
now at Moorfields. When first offered the chance to
participate, we wanted to give him everything we
could to successfully navigate the world. We also
understood the huge implications for future research,
and how participating could help others. It has been
a phenomenally positive experience, and the results are
nothing short of spectacular.
